Welcome to Wizardlancet’s

About Me

I am Zilong Wang, an AI researcher and entrepreneur with a background in clinical medicine. I recently left Microsoft Research Asia (MSRA) to build an Agent-Native Biotech company. This move grows out of my research in AI agents and human–AI interaction, and my interest in how organizations can integrate agents into their work. I see an opportunity for agents to contribute to sustained, complex collaboration and reshape how research is organized and carried forward. We have completed our seed funding round.

Our goal is to address the long timelines and high costs of drug development—often described as 10–15 years and approximately US$2.6 billion—with a particular focus on clinical development and advancement. By integrating agents into research, decision-making, and execution, we aim to help human experts and AI agents work together to shorten development timelines, reduce costs, and bring valuable medicines to patients sooner.

My research spans AI4Health, Foundation Models, and Human–AI Interaction. Previously, I was a Senior Researcher in the Machine Learning Group at MSRA in Shanghai, working on medical foundation models, autonomous agents, and human–AI collaboration. I received my M.D. in Clinical Medicine from Shanghai Medical College, Fudan University, in 2018. Before joining MSRA in 2023, I served as CTO of medical technology startups, leading AI Software as a Medical Device products through development, clinical validation, regulatory approval, and market access. These experiences ground my work in translating technical advances into demonstrable clinical value. I was recognized by Forbes China 30 Under 30 (2020) and Hurun U30 China Entrepreneurship Leaders (2021), and serve on the Executive Committee of the CCF Digital Medicine Technical Committee.

News

[Oct. 1, 2026] Our team Watt won 1st Place in both the Any-to-7T and Any-to-any tracks of the MICCAI 2026 MRIxFields Challenge.

[Sept. 5, 2026] We introduced MARLA: An Autonomous Agent for Medical AI Research and Development, our work on Medical RSI (Recursive Self-Improvement). MARLA translates clinicians’ research goals into executable research loops, coordinates code agents to develop and evaluate medical AI models, and distills experience into reusable skills to improve subsequent research workflows.

[June 16, 2026] We released scIsoAgent, our work on long-horizon autonomous agents for bioinformatics. It supports isoform-resolved characterization and sequence-informed interpretation of long-read single-cell transcriptomes, connecting multi-step analysis with biological interpretation.

[June 1, 2026] RenalCLIP was accepted by Nature Communications. This disease-centric vision-language foundation model supports precision oncology in kidney cancer through multi-task analysis of CT images. The paper was published online on June 8, 2026.

[Feb. 2026] We released OMGs (Ovarian tumour Multidisciplinary intelligent aGent System), an LLM-powered multi-agent framework designed to support MDT decision-making across the ovarian tumor care continuum. In multicenter evaluations, OMGs achieved performance comparable to expert MDT consensus, demonstrating the potential of collaborative agentic AI systems in high-stakes clinical decision support.

[Jan. 2026] Four papers accepted as ICLR 2026 posters, covering visual prompt tuning interpretability, multi-modal Alzheimer’s disease diagnosis, reasoning-driven multimodal LLM for domain generalization, and a token-level fix for low-probability over-domination in RL for LLMs.

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[Jan. 2026] Three papers accepted to top-tier venues: AAAI 2026 (medical foundation models for inner ear temporal CT analysis) and two CHI 2026 papers on accessibility and human-AI interaction for screen reader users in the vibe coding era and computer use scenarios.

[Jan. 2026] We introduced GI-Bench, a panoramic benchmark covering 20 fine-grained lesion categories to systematically evaluate Multimodal Large Language Models (MLLMs) across a five-stage gastrointestinal endoscopy clinical workflow, advancing clinically grounded evaluation of multimodal foundation models.

[Aug. 2025] We open-sourced Agent Lightning⚡, a flexible framework that enables developers to train ANY AI agent with Reinforcement Learning (RL). By decoupling agent execution from model training, it supports seamless integration with existing frameworks such as LangChain, AutoGen, and CrewAI with minimal code modification.

[Aug. 2025] We released preprints for two new medical foundation models: RenalCLIP, a disease-centric vision-language foundation model for precision oncology in kidney cancer, and DermINO, a dermatology foundation model based on a novel multi-view hybrid pretraining strategy for robust visual representation learning.

Huabu — A shared, infinite canvas where people and AI agents think and work together. Huabu brings ideas, notes, documents, and outputs from different sessions into a persistent visual Space. Users can organize information with AI, explore connections, and review proposed changes, while connected agents use both the materials and their relationships as context for ongoing work. Website & user handbook.

OpenOE-Lite — An open-source, lightweight reproduction of OpenEvidence-style evidence-based medical Q&A. With just one LLM API key and zero local vector DB, it generates grounded, citation-aligned answers in real time from OpenAlex’s 250M+ open academic works via a 6-stage pipeline (safety gate → 3-view query enhancement → multi-source retrieval → RRF dedup/rank → small-model evidence gating → grounded answer generation). The modular architecture supports smooth upgrade from the Lite core to a Full RAG with local vector DB and clinical guidelines.

Anji-Bridge 安济桥 — A PDF → AI-agent knowledge bridge that converts PDFs into structured, semantic Markdown/JSON ready for LLMs and agents. Built on PaddleOCR-VL for layout-aware OCR and Ovis2.5-9B VLM for image understanding, with AST-level enhancement (heading correction, decorative element filtering, image captioning) and multi-format export. Supports batch processing and base64-embedded portable outputs.

Mandarin Speech Prosody Benchmark (MSPB) — The companion repository for our Interspeech 2025 paper “Can AI Understand Mandarin Speech Prosody?”. MSPB is a linguistically grounded benchmark with 178 phonetically recorded and expert-validated stimuli covering 8 prosody-related tasks (tone/intonation, prosodic ambiguity, focus marking, focus operators, scalar meaning, irony, emotional prosody with/without context). It systematically evaluates how Speech LLMs interpret prosodic cues across phonology, syntax, semantics, and pragmatics.

Contact

Selected Publications

2026

  • MedCUA-Bench: A Screenshot-Only Benchmark for Clinical Computer-Use Agents.
    Yu, Jia, Wang, Zilong, Jiang, Xinyang, Li, Dongsheng, Wang, Shuo
    EMNLP 2026 (accepted), 2026 · Link · DOI
  • Thoracic Intermuscular Adiposity, Coronary Microvascular Dysfunction, and Prognosis After Cardiac Surgery.
    Zhou, You, Cui, Jie, Lu, Jinjuan, Wang, Zilong, Shen, Jinqiang, Zhou, Xiaonan, Lu, Danbo, Deng, Lixiang, Wang, Zhe, Liu, Hua, Zhang, Peipei, Hu, Yiqing , et al.
    Journal of the American Heart Association, e053125, 2026 · Link · DOI
  • Recursive Organization Improvement: A Modeling Specification for Human–Agent Organizations.
    Wang, Zilong
    arXiv preprint arXiv:2609.38643, 2026 · Link · DOI
  • Deep learning of pretreatment ascites cytopathology for platinum-resistance risk stratification in advanced epithelial ovarian cancer.
    Zhang, Yangyang, Wan, Xiaochun, Chen, Yongqi, Xu, Jianbo, Wang, Weijie, Li, Haiming, Zhang, Zhihao, Luo, Yi-Hua, Wang, Liu, Ju, Xingzhu, Wu, Xiaohua, Wang, Zilong , et al.
    Neoplasia 79:101330, 2026 · Link · DOI
  • Benchmarking Clinical Decision Pathway Adherence in Large Language Models.
    Chen, Nuo, Jiang, Xinyang, Wang, Zilong, Zhang, Zhifei, Qu, Xiaoye, Deng, Jiajun, Guo, Yulan, Zhao, Cairong
    arXiv preprint arXiv:2608.26592, 2026 · Link · DOI
  • MARLA: An Autonomous Agent for Medical AI Research and Development.
    Chen, Xueyu, Jiang, Xinyang, Song, Zifan, Shan, Caihua, Wang, Zilong, Li, Dongsheng, Zhao, Cairong
    medRxiv preprint, 2026 · Link · DOI
  • scIsoAgent enables autonomous isoform-resolved characterization and sequence-informed interpretation of long-read single-cell transcriptomes.
    Zhao, Chengzhi, Liu, Mingyu, Li, Xue, Li, Dongsheng, Xu, Yichi, Wang, Zilong
    bioRxiv preprint, 2026 · Link · DOI
  • Centering the marginalized: AI-driven strategies for advancing health equity in rare disease care.
    Lei, Chaoyu, Zuo, Ying, Lopes, Claudia Abreu, Stuart, Jaimee, Xu, Benjamin, Liu, T. Y. Alvin, Ploug, Thomas, Wang, Zilong, Dang, Kang, Jin, Kai, Yu, Haoxuan, Tatere, Heaven Yeshaneh , et al.
    Patterns 7(5):101535, 2026 · Link · DOI
  • GI-Bench: A Panoramic Benchmark Revealing the Knowledge-Experience Dissociation of Multimodal Large Language Models in Gastrointestinal Endoscopy Against Clinical Standards.
    Zhu, Yan, Luo, Te, Fu, Pei-Yao, Zhang, Zhen, Wang, Zi-Long, Qu, Yi-Fan, Geng, Zi-Han, Xu, Jia-Qi, Yao, Lu, Ma, Li-Yun, Su, Wei, Chen, Wei-Feng , et al.
    arXiv preprint arXiv:2601.08183, 2026 · Link · DOI
  • OMGs: A multi-agent system supporting MDT decision-making across the ovarian tumour care continuum.
    Zhang, Yangyang, Wang, Zilong, Xu, Jianbo, Chen, Yongqi, Han, Chu, Zhang, Zhihao, Liu, Shuai, Li, Hui, Zhang, Huiping, Liu, Ziqi, Chen, Jiaxin, Zhu, Jun , et al.
    arXiv preprint arXiv:2602.13793, 2026 · Link · DOI
  • Exploring interpretability for visual prompt tuning with cross-layer concepts.
    Wang, Yubin, Jiang, Xinyang, Cheng, De, Zhao, Xiangqian, Wang, Zilong, Li, Dongsheng, Zhao, Cairong
    ICLR 2026 (poster), 2026 · Link
  • Joint adaptation of uni-modal foundation models for multi-modal Alzheimer's disease diagnosis.
    Gu, Wentao, Li, Yuquan, Jiang, Xinyang, Wang, Zilong, Li, Dongsheng, Li, Zehui, Dong, Zijian, Zhao, Cairong
    ICLR 2026 (poster), 2026 · Link
  • Reasoning-driven multimodal LLM for domain generalization.
    Xu, Zhipeng, Wang, Zilong, Jiang, Xinyang, Li, Dongsheng, Cheng, De, Wang, Nannan
    ICLR 2026 (poster), 2026 · Link
  • Do not let low-probability tokens over-dominate in RL for LLMs.
    Yang, Zhihe, Luo, Xufang, Wang, Zilong, Han, Dongqi, He, Zhiyuan, Li, Dongsheng, Xu, Yunjian
    ICLR 2026 (poster), 2026 · Link
  • Programmers Who Use Screen Readers in the Vibe Coding Era: Adaptation, Empowerment, and New Accessibility Landscape.
    Chen, Nan, Qiu, Luna K., Wang, Arran Zeyu, Wang, Zilong, Yang, Yuqing
    CHI 2026, 2026 · Link · DOI
  • From Struggle to Success: Context-Aware Guidance for Screen Reader Users in Computer Use.
    Chen, Nan, Lu, Jing, Wang, Zilong, Qiu, Luna K., Chen, Siming, Yang, Yuqing
    CHI 2026, 2026
  • Tuning Medical Foundation Models for Inner Ear Temporal CT Analysis with Plug-and-play Domain Knowledge Aggregator.
    Wan, Weixun, Jiang, Xinyang, Wang, Zilong, Li, Bei, Zhao, Cairong
    AAAI 2026, 2026
  • A Disease-Centric Vision-Language Foundation Model for Precision Oncology in Kidney Cancer.
    Tao, Yuhui, Zhao, Zhongwei, Wang, Zilong, Luo, Xufang, Chen, Feng, Wang, Kang, Wu, Chuanfu, Zhang, Xue, Zhang, Shaoting, Yao, Jiaxi, Jin, Xingwei, Jiang, Xinyang , et al.
    Nature Communications 17:7313, 2026 · Link · DOI
  • ReMe: Scaffolding Personalized Cognitive Training via Controllable LLM-Mediated Conversations.
    Wang, Zilong, Chen, Nan, Qiu, Luna K., Yue, Ling, Guo, Geli, Ou, Yang, Jiang, Shiqi, Yang, Yuqing, Qiu, Lili
    CHI 2026 (LBW/poster), 2026 · Link · DOI

2025

  • EEGChaT: A Transformer-Based Modular Channel Selector for SEEG Analysis.
    Wang, Chen, Wang, Yansen, Han, Dongqi, Wang, Zilong, Li, Dongsheng
    arXiv preprint arXiv:2510.13592, 2025 · Link · DOI
  • Towards Ultra-low Framerate Ultrasound Localization Microscopy on Human Brain with Artificial Intelligence.
    Jiang, Xinyang, Zhong, Chuanyu, Wan, Weixun, Qu, Zefan, Wang, Zilong, Zhang, Xingxuan, Xu, Xiang, Wei, Linglin, Sun, Dailin, Wang, Yu
    Preprint, 2025
  • Can AI Understand Mandarin Speech Prosody? A Framework and Benchmark Showcase.
    Wang, Zilong, Zhang, Xiaoxue, Jiang, Xinyang, Song, Kaitao, Yu, Jue
    Interspeech 2025, 2025
  • Segmentation Helps Understanding: Mask-Infused Vision-Language Pre-training for 3D Medical Images.
    Hu, Yuqi, Luo, Xufang, Wang, Zilong
    Preprint, 2025
  • DermINO: Hybrid Pretraining for a Versatile Dermatology Foundation Model.
    Xu, Jingkai, Cheng, De, Zhao, Xiangqian, Yang, Jungang, Wang, Zilong, Jiang, Xinyang, Luo, Xufang, Chen, Lili, Ning, Xiaoli, Li, Chengxu, Zhou, Xinzhu, Song, Xuejiao , et al.
    arXiv preprint arXiv:2508.12190, 2025 · Link · DOI
  • Learning Robust Representations for Medical Images via Unifying (Self-)Supervisions.
    He, Xiaoxuan, Luo, Xufang, Yang, Yifan, Jiang, Xinyang, Wang, Zilong, Usuyama, Naoto, Zhang, Sheng, Poon, Hoifung, Yang, Yuqing, Li, Dongsheng, Qiu, Lili
    ICLR 2025 submission (OpenReview), 2025 · Link
  • Agent Lightning: Train ANY AI Agents with Reinforcement Learning.
    Luo, Xufang, Zhang, Yuge, He, Zhiyuan, Wang, Zilong, Zhao, Siyun, Li, Dongsheng, Qiu, Luna K., Yang, Yuqing
    arXiv preprint arXiv:2508.03680, 2025 · Link · DOI
  • AI-assisted facial analysis in healthcare: From disease detection to comprehensive management.
    Patterns, 2025 · Link

2024

  • Screening chronic kidney disease through deep learning utilizing ultra-wide-field fundus images.
    Zhao, Xinyu, Gu, Xingwang, Meng, Lihui, Chen, Yongwei, Zhao, Qing, Cheng, Shiyu, Zhang, Wenfei, Cheng, Tiantian, Wang, Chuting, Shi, Zhengming, Jiao, Shengyin, Jiang, Changlong, Jiao, Guofang, Teng, Da, Sun, Xiaolei, Zhang, Bilei, Li, Yakun, Lu, Huiqin, Chen, Changzheng, Zhang, Hao, Yuan, Ling, Su, Chang, Zhang, Han, Xia, Song, Liang, Anyi, Li, Mengda, Zhu, Dan, Xue, Meirong, Sun, Dawei, Li, Qiuming, Zhang, Ziwu, Zhang, Donglei, Lv, Hongbin, Ahmat, Rishet, Wang, Zilong , et al.
    npj Digital Medicine 7:275, 2024 · Link · DOI
  • DualStreamFoveaNet: A dual stream fusion architecture with anatomical awareness for robust fovea localization.
    Song, Sifan, Wang, Jinfeng, Wang, Zilong, Wang, Hongxing, Su, Jionglong, Ding, Xiaowei, Dang, Kang
    IEEE Journal of Biomedical and Health Informatics 28(12):7217–7229, 2024 · Link · DOI
  • LLM-RadJudge: Achieving Radiologist-Level Evaluation for X-Ray Report Generation.
    Wang, Zilong, Luo, Xufang, Jiang, Xinyang, Li, Dongsheng, Qiu, Lili
    arXiv preprint arXiv:2404.00998, 2024 · Link · DOI

2023

  • Early detection of visual impairment in young children using a smartphone-based deep learning system.
    Chen, Wenben, Li, Ruiyang, Yu, Qinji, Xu, Andi, Feng, Yile, Wang, Ruixin, Zhao, Lanqin, Lin, Zhenzhe, Yang, Yahan, Lin, Duoru, Wu, Xiaohang, Chen, Jingjing, Liu, Zhenzhen, Wu, Yuxuan, Dang, Kang, Qiu, Kexin, Wang, Zilong , et al.
    Nature Medicine 29(2):493–503, 2023 · Link · DOI

2020

  • Artificial intelligence-enabled screening for diabetic retinopathy: A real-world, multicenter and prospective study.
    Zhang, Yifei, Shi, Juan, Peng, Ying, Zhao, Zhiyun, Zheng, Qidong, Wang, Zilong, Liu, Kun, Jiao, Shengyin, Qiu, Kexin, Zhou, Ziheng, Yan, Li, Zhao, Dong , et al.
    BMJ Open Diabetes Research & Care 8(1):e001596, 2020 · Link · DOI